A family in route to New Guinea is shipwrecked on a deserted tropical island. They are forced to remain on the island because of the damage to the ship and the pirates that are roaming the islands. They create a home on the island (centering around a huge tree house) and explore the island and its wildlife. Plenty of adventure ensues as the family deals with issues of survival and pirates, and the brothers must learn how to live on the island with an uncertain future.

The moon rises at a predestined angle and awakens the sleeping Dr. Phibes three years later. To his dismay, he finds his house has been demolished and his papyrus scrolls stolen, the scrolls he needs to find the Pharoah's Tomb in Egypt, where the River of Life flows. After identifying the source of the papyrus theft, he packs and leaves for Egypt with his assistant Vulnavia, still intent upon awakening his dead wife Victoria. The parties responsible for the theft of Phibes' scrolls suffer an attrition problem as Inspector Trout chases him across the world.